San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway
San-Huang-Yi-Shen capsule (SHYS) has been RAMEN ASIAN VEG used in the treatment of diabetic kidney disease (DKD) in clinics.However, the mechanism of SHYS on DKD remains unclear.In this study, we used a high-fat diet combined with streptozocin (STZ) injection to establish a rat model of DKD, and different doses of SHYS were given by oral gavage to